Human Genome Epidemiology (HuGE): Translating Advances in Human Genetics into Population-based Data for Medicine and Public Health
نویسنده
چکیده
In this editorial, I highlight the role of epidemiology as a discipline that provides population-based information on the relationship between human genetic variation and various human diseases. I also invite authors to submit the results of epidemiologic investigations to Genetics in Medicine and thus to contribute to translating advances in human genetics research into medical and public health practice.
منابع مشابه
The human genome project is complete. How do we develop a handle for the pump?
A half century since the publication of the structure of the DNA molecule (2), the sequence of the human genome is complete. Some expect this achievement to be translated into advances in medicine and public health relatively rapidly (3– 6). Proponents of this approach tend to focus on the potential to tailor primary prevention, secondary prevention, or therapy on the basis of genetic informati...
متن کاملTrends in Population-Based Studies of Human Genetics in Infectious Diseases
Pathogen genetics is already a mainstay of public health investigation and control efforts; now advances in technology make it possible to investigate the role of human genetic variation in the epidemiology of infectious diseases. To describe trends in this field, we analyzed articles that were published from 2001 through 2010 and indexed by the HuGE Navigator, a curated online database of PubM...
متن کاملCommentary: epidemiology and the continuum from genetic research to genetic testing.
In January 2001, the Centers for Disease Control and Prevention and the National Institutes of Health convened an expert panel to develop recommendations for evaluating and synthesizing data from epidemiologic studies of the human genome. Experts in medicine, genetics, epidemiology, statistics, laboratory sciences, prevention effectiveness, and the social sciences discussed examples drawn from ...
متن کاملBasic Principles of Human Genetics: A Primer for Oral Medicine
Humans have known for several 1000 years that heredity affects health. However, it was only 150 years ago when Gregor Mendel first described the mechanism by which genotype results in phenotype. It was less than 100 years ago when Garrod began to apply genetic knowledge to human diseases and disorders. Ironically, for most of the 20th century, clinicians viewed genetics as a somewhat esoteric a...
متن کاملHuman Development and related Components with Malnutrition in Children: a Global Ecological Study
Background: It is necessary to get information on nutrition situation in children and epidemiology of the malnutrition to use for planning and health policy making, therefore this study aimed to identify the role of human development on nutrition situation in children under-five years of old worldwide.Methods: This ecological study was performed on the relation of the nutrition situation of chi...
متن کامل